What is the Dynamic Response and how is it defined?

The Dynamic Response (DR) is a parameter that characterizes the switching speed of DNA nanolevers. It is automatically calculated from the raw data by the switchSENSE® software package. For every recorded data point, the software evaluates typically the upward motion...

How is the Hydrodynamic Diameter defined?

The hydrodynamic diameter (Dh) of a molecule is defined as the diameter of a perfect solid sphere that would exhibit the same hydrodynamic friction as the molecule of interest. Thus, the Dh value reflects primarily the hydrodynamic friction but is usually also a good...

What is the Lollipop Model?

The so-called lollipop model is a biophysical model, which allows to simulate the behavior of end-tethered DNA-nanolevers on chargeable surfaces. It mathematically simplifies the hydrodynamic properties of DNA nanolevers with attached protein molecules by assuming...

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