During a measurement in dynamic mode, the DNA nanolevers are switched by applying an alternating voltage to the gold electrode, whereas in static mode they are kept in an upright orientation by a constant negative potential. The dynamic mode is usually used to...
Your ligand of interest can be a single-strand RNA or DNA sequence, a double-strand RNA or DNA sequence, an aptamer, a small molecule, a protein or peptide of any desired size, a liposome, a virus-like particle, or whatever else you can think of. If you have questions...
Your analyte of interest can be anything ranging from small molecules to peptides and proteins and even multispecific binders like antibodies or PROTACs. If you have questions concerning the applicability of your specific analyte, contact our specialists!
switchSENSE® is a very versatile technology and offers comprehensive biophysical information. You can measure the following parameters: Kinetics (association rate kon, dissociation rate koff) Affinity, Avidity (Kd) Dose response (EC, IC50) Multispecific interactions...
The heliX+ is equipped with 2 lasers and 4 single-photon counters. This allows to collect signals from two different fluorescent dyes for each of the two measurement spots. You have many options to use this for your specific assay requirements: Multiplex and measure 4...
