switchSENSE®

eLearning Center

We cover an array of various, different applications.
Browse through publications, application notes,
tutorials, and more.

DNA/RNA Binders

Measure the kinetics and affinities of DNA/RNA binding proteins directly with switchSENSE®’s unique DNA nanolever approach.

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Antibodies / Bispecifics

Unravel the behaviour of complex binders like antibodies and other bispecifics with switchSENSE®’s versatile binding assays.

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Conformation & Size

Solve the structure=function equation and study conformational changes in real-time with switchSENSE®’s dynamic measurement mode.

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HIGHLIGHTING

Multiplex DNA-Binder Tutorial

In this 20 min tutorial, learn how easy it is to measure kinetics of a DNA-binding protein to 4 targets simultaneously with our new heliX® biosensor.

We are analyzing association and dissociation rates, and KD values to understand how changes in a target DNA sequence, the T7 promoter, affect T7 RNA polymerase binding kinetics. Watch the video to learn how heliX® enables you to multiplex your molecular interaction studies in a user friendly, cost effective, and reproducible way.

Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease

Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease

Physical interaction between the strawberry allergen Fra a 1 and an associated partner FaAP: Interaction of Fra a 1 proteins and FaAP.

Physical interaction between the strawberry allergen Fra a 1 and an associated partner FaAP: Interaction of Fra a 1 proteins and FaAP.

Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy I Paper

Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy I Paper

Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition.

Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition.

Advanced biophysical analysis of mono and bispecific antibody formats

Advanced biophysical analysis of mono and bispecific antibody formats

Biophysical analysis of liposomes and antibody-receptor interactions on VLPs

Biophysical analysis of liposomes and antibody-receptor interactions on VLPs

Biophysical analysis of Cas9-DNA interactions and enzymatic activity

Biophysical analysis of Cas9-DNA interactions and enzymatic activity

Hydrodynamic diameter and thermal stability measurements of protein kinase A

Hydrodynamic diameter and thermal stability measurements of protein kinase A

switchSENSE: A new technology to study protein-RNA interactions

switchSENSE: A new technology to study protein-RNA interactions

Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.

Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon.

The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence.

The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence.

Contact Us

Discuss your specific needs with our specialists.

info@dynamic-biosensors.com

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