switchSENSE®

eLearning Center

We cover an array of various, different applications.
Browse through publications, application notes,
tutorials, and more.

DNA/RNA Binders

Measure the kinetics and affinities of DNA/RNA binding proteins directly with switchSENSE®’s unique DNA nanolever approach.

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Antibodies / Bispecifics

Unravel the behaviour of complex binders like antibodies and other bispecifics with switchSENSE®’s versatile binding assays.

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Conformation & Size

Solve the structure=function equation and study conformational changes in real-time with switchSENSE®’s dynamic measurement mode.

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HIGHLIGHTING

Multiplex DNA-Binder Tutorial

In this 20 min tutorial, learn how easy it is to measure kinetics of a DNA-binding protein to 4 targets simultaneously with our new heliX® biosensor.

We are analyzing association and dissociation rates, and KD values to understand how changes in a target DNA sequence, the T7 promoter, affect T7 RNA polymerase binding kinetics. Watch the video to learn how heliX® enables you to multiplex your molecular interaction studies in a user friendly, cost effective, and reproducible way.

Specialized interfaces of Smc5/6 control hinge stability and DNA association

Specialized interfaces of Smc5/6 control hinge stability and DNA association

Molecular dynamics of DNA–protein conjugates

Molecular dynamics of DNA–protein conjugates

Detection of the carcinogenic water pollutant Benzo[a]pyrene

Detection of the carcinogenic water pollutant Benzo[a]pyrene

Protein analysis by time-resolved measurements

Protein analysis by time-resolved measurements

Polymerase/DNA interactions and enzymatic activity

Polymerase/DNA interactions and enzymatic activity

switchSENSE® for characterization of polymerases

switchSENSE® for characterization of polymerases

A straightforward method to conjugate antibodies to oligonucleotides – preparation, purification and their applications

A straightforward method to conjugate antibodies to oligonucleotides – preparation, purification and their applications

Binding theory: equations for affinity and kinetics analysis

Binding theory: equations for affinity and kinetics analysis

Kinetic measurements and comparison with Biacore and solution data

Kinetic measurements and comparison with Biacore and solution data

Repeatability of binding kinetics measurements and regeneration performance

Repeatability of binding kinetics measurements and regeneration performance

Association rate of two equimolar reactants in solution

Association rate of two equimolar reactants in solution

Contact Us

Discuss your specific needs with our specialists.

info@dynamic-biosensors.com

+49 89 89 74 544-0

Lochhamer Str. 15, 82152 Martinsried/Planegg, Germany

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