We cover an array of various, different applications.
Browse through publications, application notes,
tutorials, and more.
Measure the kinetics and affinities of DNA/RNA binding proteins directly with switchSENSE®’s unique DNA nanolever approach.
Antibodies / Bispecifics
Unravel the behaviour of complex binders like antibodies and other bispecifics with switchSENSE®’s versatile binding assays.
Conformation & Size
Solve the structure=function equation and study conformational changes in real-time with switchSENSE®’s dynamic measurement mode.
Multiplex DNA-Binder Tutorial
In this 20 min tutorial, learn how easy it is to measure kinetics of a DNA-binding protein to 4 targets simultaneously with our new heliX® biosensor.
We are analyzing association and dissociation rates, and KD values to understand how changes in a target DNA sequence, the T7 promoter, affect T7 RNA polymerase binding kinetics. Watch the video to learn how heliX® enables you to multiplex your molecular interaction studies in a user friendly, cost effective, and reproducible way.
Specialized interfaces of Smc5/6 control hinge stability and DNA association
Molecular dynamics of DNA–protein conjugates
Detection of the carcinogenic water pollutant Benzo[a]pyrene
Protein analysis by time-resolved measurements
Polymerase/DNA interactions and enzymatic activity
switchSENSE® for characterization of polymerases
A straightforward method to conjugate antibodies to oligonucleotides – preparation, purification and their applications
Quantifying DNA exonuclease activity
Binding theory: equations for affinity and kinetics analysis
Kinetic measurements and comparison with Biacore and solution data
Repeatability of binding kinetics measurements and regeneration performance
Association rate of two equimolar reactants in solution
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