switchSENSE®

eLearning Center

We cover an array of various, different applications.
Browse through publications, application notes,
tutorials, and more.

DNA/RNA Binders

Measure the kinetics and affinities of DNA/RNA binding proteins directly with switchSENSE®’s unique DNA nanolever approach.

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Antibodies / Bispecifics

Unravel the behaviour of complex binders like antibodies and other bispecifics with switchSENSE®’s versatile binding assays.

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Conformation & Size

Solve the structure=function equation and study conformational changes in real-time with switchSENSE®’s dynamic measurement mode.

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HIGHLIGHTING

Multiplex DNA-Binder Tutorial

In this 20 min tutorial, learn how easy it is to measure kinetics of a DNA-binding protein to 4 targets simultaneously with our new heliX® biosensor.

We are analyzing association and dissociation rates, and KD values to understand how changes in a target DNA sequence, the T7 promoter, affect T7 RNA polymerase binding kinetics. Watch the video to learn how heliX® enables you to multiplex your molecular interaction studies in a user friendly, cost effective, and reproducible way.

Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications I App Note

Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications I App Note

CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells I Paper

CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells I Paper

A DNA-based biosensor assay for the kinetic characterization of ion-dependent aptamer folding and protein binding I Publication

A DNA-based biosensor assay for the kinetic characterization of ion-dependent aptamer folding and protein binding I Publication

Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines

Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines

Magnesium-Dependent Electrical Actuation and Stability of DNA Origami Rods

Magnesium-Dependent Electrical Actuation and Stability of DNA Origami Rods

Tailored peptide phenyl esters block ClpXP proteolysis by an unusual breakdown into a heptamer‐hexamer assembly

Tailored peptide phenyl esters block ClpXP proteolysis by an unusual breakdown into a heptamer‐hexamer assembly

switchSENSE® – Biophysical Analysis with Electro-Switchable Biosurfaces

switchSENSE® – Biophysical Analysis with Electro-Switchable Biosurfaces

A new biosensor-based assay for aptamer-protein interaction analysis I App Note

A new biosensor-based assay for aptamer-protein interaction analysis I App Note

High-affinity capturing of antibodies on the switchSENSE® biochip  using CaptureSelect™ affinity ligands

High-affinity capturing of antibodies on the switchSENSE® biochip using CaptureSelect™ affinity ligands

Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant

Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant

Contact Us

Discuss your specific needs with our specialists.

info@dynamic-biosensors.com

+49 89 89 74 544-0

Lochhamer Str. 15, 82152 Martinsried/Planegg, Germany

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