switchSENSE®

eLearning Center

We cover an array of various, different applications.
Browse through publications, application notes,
tutorials, and more.

DNA/RNA Binders

Measure the kinetics and affinities of DNA/RNA binding proteins directly with switchSENSE®’s unique DNA nanolever approach.

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Antibodies / Bispecifics

Unravel the behaviour of complex binders like antibodies and other bispecifics with switchSENSE®’s versatile binding assays.

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Conformation & Size

Solve the structure=function equation and study conformational changes in real-time with switchSENSE®’s dynamic measurement mode.

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HIGHLIGHTING

Multiplex DNA-Binder Tutorial

In this 20 min tutorial, learn how easy it is to measure kinetics of a DNA-binding protein to 4 targets simultaneously with our new heliX® biosensor.

We are analyzing association and dissociation rates, and KD values to understand how changes in a target DNA sequence, the T7 promoter, affect T7 RNA polymerase binding kinetics. Watch the video to learn how heliX® enables you to multiplex your molecular interaction studies in a user friendly, cost effective, and reproducible way.

switchSENSE® Fluorescence Proximity Sensing – in static mode

switchSENSE® Fluorescence Proximity Sensing – in static mode

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

switchSENSE® Analysis of Protein Diameters and Conformational Changes

switchSENSE® Analysis of Protein Diameters and Conformational Changes

Assembly and Characterization of a Slingshot DNA Nanostructure for the Analysis of Bivalent and Bispecific Analytes with Biosensors

Assembly and Characterization of a Slingshot DNA Nanostructure for the Analysis of Bivalent and Bispecific Analytes with Biosensors

DNA Primer Extension with Cyclopropenylated 7-Deaza-2′-deoxyadenosine and Efficient Bioorthogonal Labeling in Vitro and in Living Cells

DNA Primer Extension with Cyclopropenylated 7-Deaza-2′-deoxyadenosine and Efficient Bioorthogonal Labeling in Vitro and in Living Cells

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

Electrical actuation of a DNA origami nanolever on an electrode

Electrical actuation of a DNA origami nanolever on an electrode

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

High-affinity capturing of tagged proteins on the switchSENSE® biochip using Strep-Tactin®XT

High-affinity capturing of tagged proteins on the switchSENSE® biochip using Strep-Tactin®XT

A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding

A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding

Contact Us

Discuss your specific needs with our specialists.

info@dynamic-biosensors.com

+49 89 89 74 544-0

Lochhamer Str. 15, 82152 Martinsried/Planegg, Germany

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